Interdisciplinary Projects

Untargeted Metabolomic Profiling of Early Diet Energy Intake in C57BL/6N Mice Indicates Tentative Differences Associated with Diet and Aberrant Crypt Foci Presence

Haley Chatelaine (PhD)

Advisor:
Rachel Kopec (OSU Nutrition Program) (Interdisciplinary)

High-fat (H) and calorie-restricted (E) diets are associated with increased and reduced risk for colorectal cancer (CRC), respectively. Metabolomes associated with H- vs. E-associated CRC risk have never been directly compared, nor has how these diets influence proximal (PC), medial (MC), and...
Using Metabolomics to Classify the Underlying Effects of Multi-Nutrient Supplementation in ADHD Youth

Madeline Stern (MS)

Advisor:
Rachel Kopec (OSU Nutrition Program) (Interdisciplinary)

Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric disorder with increasing global prevalence and high heritability commonly diagnosed in childhood. Current pharmaceutical treatment options provide a poor long-term risk:benefit ratio with little knowledge of the long-term...
Iron Chlorophyllin Bio-efficacy and Metabolites Following Simulated Digestion and Incubation with Caco-2 cells

Siqiong Zhong (PhD)

Advisor:
Rachel Kopec (OSU Nutrition Program) (Interdisciplinary)

Developing countries rely on poorly bioavailable plant-based sources of iron (i.e.FeSO4), leading to iron deficiency anemia. Heme iron is more bioavailable, but predominantly found in red meat. Iron chlorophyllin (IC) utilizes the porphyrin ring of plant-based chlorophyll to bind iron. IC has...

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Interdisciplinary Projects

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Untargeted Metabolomic Profiling of Early Diet Energy Intake in C57BL/6N Mice Indicates Tentative Differences Associated with Diet and Aberrant Crypt Foci Presence

Using Metabolomics to Classify the Underlying Effects of Multi-Nutrient Supplementation in ADHD Youth

Iron Chlorophyllin Bio-efficacy and Metabolites Following Simulated Digestion and Incubation with Caco-2 cells